Accompanied by his wife Samantha, Mr Cameron made a speech outside Downing Street on Friday morning (24 June), after the results were confirmed, saying "fresh leadership" was needed.
Scotty T, Geordie Shore star
DAVID CAMERON RESIGNS!!!!! #BREXIT— Scotty T (@ScottGShore) June 24, 2016
Luisa Zissman, reality star
NO! David Cameron has now resigned.... Who will be our next conservative PM? #EUref— Luisa Zissman (@TheLuluLife) June 24, 2016
Deano Baily, Ibiza Weekender star
So just like my ex birds. Cameron leaves us just when we need him most— Deano Baily (@DeanoWeekender) June 24, 2016
Jake Humphrey, TV presenter
Cameron has gone.— Jake Humphrey (@mrjakehumphrey) June 24, 2016
The first example of unemployment rising post #Brexit.
Jemima Goldsmith, journalist
Friends on both the left and the right sad to see David Cameron resign today, given the alternatives. Ducking depressing.— Jemima Goldsmith (@Jemima_Khan) June 24, 2016
Sarah Harding, Girls Aloud singer
Duncan James, Blue singer
Well I guess the nation has spoken! Who will be PM now ?? #BorisJohnson ??— Duncan James (@MrDuncanJames) June 24, 2016
Kirk Norcross, ex-TOWIE star