Geordie Shore star Scott hit out at the couple - who he lived with in the CBB house earlier this year - saying they had "gone off the rails".
While former Hollyoaks actress Stephanie hasn't publicly responded to Scott's surprising comments, she did like a tweet by a fan, which suggests their friendship is well and truly over.
Steph liked a tweet, which read: "He is sly as a snake...clocked him being shady in the bb house, he was never their mate."
Scott had told Bang Showbiz: "I don't want to be friends with them because I feel as if they have gone off the rails. I mean Jeremy, when he left Big Brother, apparently he said some things about me. He was like 'Scott's been getting with Megan [McKenna] but he's got a girlfriend.' She's not my girlfriend, it's just a girl I have been meeting."
While Scott said Jeremy "is not doing himself any favours", he said: "Steph just does my head in because she is a liar."
A rep for Stephanie said in response: "We don't need to give any comment on this."
Scott's comments come as Steph and Jeremy are now back together following their second split.
They rekindled their romance in Spain having hit the rocks two week ago after Steph learned Jeremy had slept with club dancer Caroline Pope in Newcastle. He also admitted to sleeping with another woman the day after he split with Steph.
Now back together, the pair have vowed to seek counselling to sort out their relationship, and Jeremy has said that Steph is the girl he wants to marry.
Steph and Jeremy found love on CBB, making their romance much-talked about in the house, especially because she was in a relationship with model Sam Reece on the outside.
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