The visual for the stunning ballad is black and white and stars American actress Nicola Peltz, but fans have already been drawing comparisons to Nicola and Zayn's ex-girlfriend, Little Mix star Perrie Edwards.
The video premiered exclusively on Apple Music but Zayn shared a teaser via Twitter.
It's a very different video from his first, 'Pillowtalk', which was rather steamy and sexy, and featured his girlfriend Gigi Hadid.
Former One Direction star Zayn first performed 'It's You' live on The Tonight Show showcasing his vocal talents and songwriting skills.
'It's You' and 'Pillowtalk' will appear on his forthcoming debut album Mind of Mine, which will be released on 25 March.
'Pillowtalk' actually went straight in at Number 1 on the UK music charts, and it also charted higher than any other song ever released by One Direction in the US.
Will 'It's You' have similar success?
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