The Keeping Up With The Kardashians star broke up with her basketball player beau a few weeks ago, according to reports in Us Weekly.
Khloe first stepped out with the 26-year-old in July last year, but decided to call time on the relationship "weeks ago" the source explained.
Fans suspected the romance was over when Khloe posted a cryptic post on Instagram in January, which read: "Stay away from people who make you feel like you are hard to love," and more recently told followers she believes "everything happens for a reason."
In the past Khloe has credited James as being "great" in supporting her after her estranged husband Lamar Odom was found unresponsive in a Nevada brothel back in October, and appreciated the fact she could be totally honest with him about the "weird situation" as she helped Lamar get back on track.
Speaking on Ryan Seacrest's radio show around the same time, Khloe told listeners: "James has been great. He's been very supportive with everything. "There's of course times where I'm sure he was really uncomfortable about some of the things, but I'm a very honest person and I have nothing to hide and I was very open with how I feel like I had to handle everything with Lamar.
"I really, really appreciate how supportive James has been, and it wasn't just another layer of stress on me. He has been great and I've been open and honest. At first there was definitely a transition period for all of us. It was a weird situation and I've never been in that before. It was trying to make everybody happy and comfortable at the same time.
Khloe has continued to support Lamar after he was discharged from hospital. The former NBA player joined Khloe and sister Kim Kardashian on a hike in Los Angeles recently, and Lamar has also moved nearby the family.
A source told E! news: "When Lamar isn't in physical therapy he is with Khloe. They continue to be closer than ever. No one really knows what will happen with them in the future.
"Lamar has a very positive attitude - Khloe is so proud of him. She encourages and motivates him everyday."
However the Us Weekly source confirmed there's no romance between the couple, despite the fact they're still technically married.
"She just wants the best for him," the insider said.
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