The 47-year-old actor was the target of Tiffany's affections in the house, as she told him: "You're so sexy. I try to deny it though but you're so masculine in your looks and the way you just speak and everything about you."
He reminded her he was happily married.
Appearing on ITV's Loose Women today, Darren said of the incident: "The thing is, sometimes things in the house that are little like that, and on the outside world would seem like nothing, magnify ten fold. And I just feel...
"What got me was we had a conversation, she said 'I find you sexy and masculine' and I said I was very flattered but I'm happily married and I'm a one woman man. What got me the most was the following night, 24 hours later, she said in a truth or dare game have you ever fantastised about cheating on your wife? I just thought that was a little bit inappropriate."
Panellist Katie Price told him: "You handled it well. It was as if she was testing you."
As for whether Darren's wife Stephanie met Tiffany at the CBB after party, he joked: "She didn't turn up! I think my wife was ready! Don't mess with her!"
Stephanie told Loose Women last week: "Well, to be honest with you, I did find the first one a little bit hysterical. The second time I was watching with my 17 year-old son and at that point I wanted to drag her through that telly! The after show party will be interesting, won't it?"
Tiffany, meanwhile, told Darren in the house that she didn't mean to disrespect him.
"I thought we was cool, maybe I did let you in on some emotions that I shouldn't have told you about. When I told you I was horny, I wasn't trying to be inappropriate with you Darren, you could have said 'Tiff you know what, I don't want to hear about that,'" she said.
"You is an attractive man, maybe when I said that I was being a little bit mischievous and scandalous. You are hot! But I didn't mean no disrespect."