Taking to Twitter, Spencer Matthews' former flame cryptically told followers she wasn't paying any attention to the girls' latest remarks.
She tweeted: "We have a limited number of f***s to give in life; pay attention to where & whom you give them too. Make them count."
Her tweet comes after Louise and Binky slammed Lauren in a recent interview.
While speaking to the Mail Online, Louise claimed: "Lauren has an agenda – she's fame hungry and has no intention of leaving the limelight."
Binky then revealed that Lauren had been calling her, but suggested she was "clutching at straws" by trying to stay in contact.
Lucy Watson also had her say, revealing Lauren had been ringing her too, but only to find out information about Spencer.
"[Lauren] has called me several times but I haven't answered," she said. "She needs to deal with [the split] on her own... she's only calling me now because she wants to know information about Spencer."
Fans were surprised to hear that Spencer and Lauren had split last month.
At the time, Spencer's rep confirmed he was single, but Lauren continued to share loved-up Instagrams of the pair, suggesting otherwise.
Now, Spencer has revealed the pair are no longer together. He said: "Lauren is lovely, but I didn't see a future with her... We had an adult conversation about it."
Fans of MIC will see a single Spenny back on their screens when the show returns next week. And not ruling out the chance of finding romance all over again, Spencer has teased: "I am enjoying myself as one would... I am single now, so I can't rule out dating someone new."
Made In Chelsea returns Monday 19 October at 9pm on E4.
For exclusive competitions and amazing prizes visit Reveal's Facebook page NOW!