Chat show host Jeremy spoke of his "sadness" and "regret" at the break-up as he confirmed their split in a statement.
"After 13 years of a generally happy marriage, my wife and I, Carla, have separated amicably," he told The Sun. "We have sadly grown apart over recent years and been living apart since earlier this summer."
Jeremy , who has three children with Carla, said the pair would continue to provide their children with a "stable upbringing" in what is "inevitably upsetting circumstances".
Just three months ago, Jeremy made an admission on his ITV chat show, about his sex life.
On The Jeremy Kyle Show, a female guest told Jeremy: "Listen, I get sex from [my boyfriend] whenever I want. I don't need to go and get sex from someone else." Jeremy replied: "Tell him then! I've had enough about talking about it. I haven't had sex for ages myself."
In 2012, Jeremy and Carla went through a difficult time when he was diagnosed with testicular cancer, but Jeremy praised his wife for being a huge support through it all.
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