Radio 1 host Fearne shared a teaser picture of tonight's episode and she looks far from impressed as Keith - real name Leigh Francis - puckers up for a smooch.
Fearne tweeted this afternoon: "When things take a turn for the worse on tonight's Celebrity Juice and I wonder how the hell I ended up like this..."
The official Celeb Juice account also said: "It happened! After 12 series @Fearnecotton & @lemontwittor finally kissed!" Sounds like a momentous occasion!
The smooch seemed to make Keith rather happy though, who said: "Me and Fearne = friends with benefits!!!! Yeah boi!"
You can watch the kiss here!
Joining Fearne as team captain this week is Gino D'Acampo. This week's celebrity guests include Strictly's Alison Hammond, comedian Johnny Vegas and TOWIE's Chloe Sims.
Celebrity Juice continues tonight (Thursday 2 October) at 10pm on ITV2.
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