The Gravity star, 53, had been jokingly referred to as Hollywood's most famous bachelor for decades... But now, he is finally off the market!
And British human rights lawyer Amal Alamuddin, 36, is one lucky lady!
George and Amal tied the knot on Saturday (27 September) in a celebrity-filled ceremony in the super romantic Italian city of Venice.
The groom arrived to his nuptials in a boat, looking heartbreakingly handsome in a black tuxedo.
The A-list guests included actors Matt Damon, Bill Murray, Emily Blunt and her husband John Krasinski, model Cindy Crawford, Vogue editor-in-chief Anna Wintour and singer Bono.
Cindy's husband Rande Gerber was George's best man at the wedding, which took place at the luxury Aman hotel.
The Venice wedding has been called a 'private symbolic ceremony', before they make it official and file the paperwork on Monday.
Congratulations to the happy couple!
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See the other celebrity couples who have married in 2014:
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