Ugly Betty star America was targeted by journalist Vitalii Sediuk at the premiere of How To Train Your Dragon 2 last month. He ran onto the red carpet and tried to shove his head underneath the folds of her gown before co-stars and security stopped him.
The shocking moment was caught on camera and broadcast around the world.
Speaking on ITV's Lorraine today, the actress said: "It was shocking and upsetting and not what we were there for. I tried to focus on what we there to do, which was to share this beautiful film with an audience and enjoy being at Cannes which I think for anyone is a really exciting moment in their career."
America added that she didn't let the disgusting behaviour ruin her big moment on the red carpet.
The brunette star is in the UK to promote new animated movie How To Train Your Dragon 2, but she also took time out on Lorraine to reminisce about her time on Ugly Betty.
"She was amazing and such a big party of my life. I was 21 when I started playing her and I'm 30 now. I grew up playing her and it's so wonderful to know people are still watching the show and discovering her. And it all ended here. We shot our last scenes on the streets of London."
As for a future reunion, she teased: "I think it's always possible. It's so wonderful to know the fan base is still excited to see more and passionate about the characters. As long as there is that love for the show, it's always possible to come back and do more."
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Watch the trailer for How To Train Your Dragon 2 below: