The Big Bang Theory star couldn't contain her excitement at being Mrs Sweeting when she took to the stage to accept the award for 'Favourite Comedic TV Actress'.
"This is the second best thing that's happened to me this year!" she gushed, before telling Ryan – who was sitting in the front row: "The first was marrying you, baby, I love you."
Kaley and tennis player Ryan tied the knot at a ranch in Southern California on New Year's Eve.
The couple had been dating for just three months before announcing their engagement in September, but defended their whirlwind courtship as something that was right for them.
Kaley walked down the aisle in a custom-designed pink Vera Wang wedding dress at the fire and ice-themed ceremony, which featured the coolest wedding cake we've ever seen: an upside down, chandelier-esque creation.
Yes, really. The unique treat was created by The Butter End Cakery in Los Angeles and flavoured with almond, chocolate and cherry. No, we don't know either how they managed to cut it.
Kaley is clearly still reveling in her newlywed status as she's been keeping fans thrilled by uploading pictures and video from her big day to Twitter.
And for anyone tiring of all the wedding talk she has just one thing to say. "My wedding day was the greatest day of my life. If you don't want to see anymore pics or video, then kindly stop following me :) cheers!!"
Kaley has now changed her Twitter name to Kaley Cuoco Sweeting.