Louise aired her views after watching Monday's episode, in which Spencer declared that Louise still has feelings for him and claimed that she messages him all the time.
Spencer's revelation came as a blow to Louise's ex Andy Jordan, who explained that Spencer has always been a "massive problem" in their relationship.
Taking to Twitter last night (12 November), Louise said: "Just watched the episode, Spencer Matthews is such a moronic human being. Anything alluding to me still having feelings for him is horribly incorrect."
Spencer's other ex, Lucy Watson, also got involved and tweeted Louise: "@LouiseAThompson Haha. And you text him all the time! (yeah like one text we now find out)."
Louise replied to Lucy: "@imLucyWatson he is literally the devil. Urgh."
Louise's tweets didn't rile Spencer though, who attempted to make light of the situation. He said: "@LouiseAThompson Relax it's just a TV show.. I wonder what happens next.."
On Monday's show, former arch rivals Louise and Lucy also put their differences aside to inform Stephanie Pratt that Spencer had cheated on her.
And next week, it appears that Spencer stirs up more trouble between Andy and Louise, while Louise is also left in tears after seeing Andy on a date with another girl!
Trouble always seems to follow love rat Spencer, so we can't wait to see what happens next!
Made In Chelsea continues on Monday 18 November at 10pm on E4.
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Check out the trailer for next week's show below: