The video clip begins with James 'Arg' Argent telling Joey Essex and Tom Pearce on the plane that "American women like bigger men".
It then shows the girls popping open a bottle of champagne in their luxury hotel suite and the boys gambling in a Vegas casino.
While sitting by the pool, Lucy Mecklenburgh hints that something is going on between two cast members behind everyone else's backs.
She says: "If it's true it will probably never come out because they're both secret squirrels and they'll keep it to themselves." Intriguing!
The Only Way Is Vegas kicks off on Sunday night (6 October) and ahead of the show's launch, some of the cast have spilled the beans to Reveal!
Despite her whispers about her co-stars, Lucy has admitted to having a holiday romance herself while in Vegas!
Meanwhile, Ferne McCann has described the trip to Sin City as "explosive", adding that there was "so much drama".
We can't wait!
The Only Way Is Vegas, 10pm, ITV2, Sunday 4 October
Watch the TOWIV trailer here: