According to Hollywood Life, the estranged couple are believed to have spoken to one another at the home they share in Los Angeles earlier this week and no doubt both stars had a lot to get off their chest.
However, although Khloe might still be wearing her wedding ring, her social media presence is beginning to get fans wondering if perhaps she and Lamar could be heading for a split.
The reality TV star recently dropped her hubby's surname from her Instagram account and it is now gone from her Twitter profile too.
Instead of her name reading 'Khloe Kardashian Odom', it now simply says 'Khloe'.
The 29-year-old also appeared to hint at her heartache on Tuesday (1 October) by uploading a picture of the ocean and writing: "I crave a love so deep the ocean would be jealous."
And she has been sharing her thoughts on love and misery on Twitter during the early hours of this morning (3 October) too.
Khloe most recently tweeted: "Promise me you'll always remember: you're braver than you believe. I am brave because of you. The love you gave made me brave. All we need is love #KKO"
The message came after she had held a chat with her followers on Twitter, so it has been assumed that she is speaking to her millions of fans.
Although, it is interesting to note that she still considers her initials ('KKO') to include Lamar's surname.
Khloe also tweeted this morning: "Keep away from people who try to belittle your ambitions. Never allow anyone to take YOUR spirit away from you. Misery loves company."
The Kardashian sister has been putting on a brave face over the last couple of months amid constant speculation that she and Lamar are on the verge of a divorce. Neither she nor Lamar have commented.
Yesterday, she distracted herself from the rumours by indulging in some retail therapy with her younger sister Kylie Jenner.
The two girls and mother Kris Jenner were spotted browsing the racks at the Kitson store in LA and of course, they were dressed to impress.
Khloe looked cute in a beige shirt, suede heels and ripped jeans, while Kylie slightly co-ordinated with her sister in a pastel coloured coat.
It's clear that Khloe is valuing having such a large and tight-knit family during this tough time, as she referred to 16-year-old Kylie as her BFF yesterday.
She wrote on Instagram: "Sisters by blood, ride or die by choice! #BFF."