Jesy Nelson, Perrie Edwards, Jade Thirlwall and Leigh-Anne Pinnock shared the exciting news via Twitter on Monday evening (30 September), saying they'll join Demi on the road in 2014.
They tweeted: "Can't believe we're going to be touring with Demi Lovato in the US next year! We're so excited! We've missed our American Mixers!"
Little Mix received an amazing reception in the States earlier this year, where they met fans and performed on massive US breakfast show Good Morning America.
And all the promotion paid off as they made chart history with album DNA, which was named the fastest-selling debut album by a British girl group in the States – even beating the Spice Girls!
Little Mix will have a little slice of the UK on tour with them too, as fellow X Factor star Cher Lloyd will also be supporting Demi.
In fact, it's going to be an X Factor extravaganza, as Demi's third support is the band Fifth Harmony, who appeared on the last series of the US X Factor, where Demi currently serves as a judge.
Demi confirmed the lineup yesterday, tweeting: "So excited that @LittleMixOffic @FifthHarmony and @CherLloyd will be joining me on #TheNeonLightsTour!!! #GIRLPOWER."
Chatting on Ryan Seacrest's KIIS-FM radio show, Demi added: "I think it's going to be so much fun. There's nothing better than woman empowerment and having an all-girls tour. What's ironic is we are all from The X Factor and that wasn't even planned. It just kind of happened that way."
Watch Little Mix's video for 'Wings' below: