Jesy, 22, was at the Essex leg of the event with fellow Little Mixer Leigh-Anne Pinnock, while George was there with all of his bandmates.
On Saturday night (17 August), the pair were spotted catching up with each other in the VIP Virgin Media Louder Lounge - and soon they were giggling and cuddling. Oo-err!
Wearing a pair of leather dungarees and a black cropped top, Jesy was all smiles as she laughed and joked with 20-year-old George in the bar area.
George, meanwhile, who kept it casual in a denim shirt and woolly hat, wasn't afraid to put his hands on Jesy's waist either as they got to know each other a little better!
The boy band star has made no secret of the fact he fancies Jesy - who shot to fame in 2011 when Little Mix won The X Factor.
When recently asked who he has his eye on, George admitted: "Jesy from Little Mix. Please put that, so I can meet her."
In June, George got his wish when he was invited to Jesy Nelson's 22nd birthday.
Jesy broke up with her boyfriend, Diversity member Jordan Banjo, earlier this year so watch this space - there could be a budding new romance on the cards!
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Check out all the pictures from Virgin Media's V Festival in our gallery!