The 'Wings' singer told her Twitter followers Nina mistook her for a friend at the Teen Choice Awards in Los Angeles on Sunday (12 August).
Jade tweeted: "Enjoyed being groped by Nina Dobrev who thought I was a friend til I turned round n she was mortified bless her! #happenstothebestofus."
Little Mix, which includes Jesy Nelson, Leigh-Anne Pinnock and Perrie Edwards, rubbed shoulders with a host of Hollywood's biggest stars at the glitzy bash at the Gibson Amphitheatre, including Selena Gomez, the Glee cast and fellow Brits One Direction and Ed Sheeran.
However, the one person that really made the girls excited was 'Heart Attack' singer Demi Lovato.
Jade tweeted: "Teen Awards was such an incredible experience! Starstruck by Demi Lovato!"
The group later posed for a picture with Demi – who is a judge on X Factor US – and X Factor US band Fifth Harmony.
Little Mix, who have been steadily building up a profile in the US recently, jetted back to the UK straight after the ceremony.
Lea Michele, One Direction, more: Teen Choice Awards 2013 pictures:
Copyright: WENN Nikki Nelson
Watch Little Mix's video for 'Wings' below: