On Wednesday (31 July), the America's Next Top Model judge appeared as a guest on music countdown show, 106 & Park, and surprised viewers by locking lips with the young male host.
Bow Wow recently put his music career on hold to present the popular BET show and we bet he's not regretting that decision at all after Tyra, 39, treated him to a kiss in front of the entire studio audience - and the nation!
The 26-year-old is known to have had a crush on Tyra for a number of years and seemed eager to get close to her yesterday, as he spritzed his mouth with breath freshener while she sat beside him on the 106 & Park sofa.
However, this isn't the first time the pair have kissed, as the outspoken supermodel made Bow Wow's dreams come true back in 2009 when he appeared on her talk show and received a peck on the lips.
Joking about whether Bow Wow was "trying to do the remix" yesterday, Tyra was seen swinging her legs onto his lap and then going in for a smooch - much to Bow Wow's surprise.
Later that evening, the rapper couldn't resist sharing his delight with his fans and flooded his Twitter with tweets and pictures.
He tweeted: "Im the man", swiftly followed by: "TYRA KISS MY LIPS TWICE".
Earlier in the day, Tyra had teased the young host by posting a photo of her 'TB' initial earrings, which she joked could also stand for "Tyra & Bow Wow".
She tweeted: "These stand 4my name or Tyra&BowWow? @106andPark 2day shud give u answer."
It certainly did!
Would you kiss a younger man? Let us know in the comment box below, as the best comment each week wins £50!