After months of speculation, Denise's spokesperson has revealed: "Denise Van Outen and Lee Mead are sad to confirm they have decided to separate.
"The couple remain the best of friends, with their daughter Betsy as their number one priority. The family ask for privacy at this time."
Up until now, Denise and Lee have both denied rumours their marriage was in trouble after rarely being spotted together.
The pair fell in love when Lee was a contestant on Any Dream Will Do in 2007, which Denise was judging.
They went on to marry in the Seychelles in 2009 and welcomed daughter Betsy a year later, who is now three.
The family were last seen together at Hamley's toy store in London - and smiled for the cameras despite living separate lives.
Lee has been pursuing a career in the US, while Denise - who is the narrator of TOWIE - is a weekend DJ for Magic 105.4.
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