The Coronation Street star, 30, witnessed the "very scary" accident on the M60 on Friday (26 June).
The singer acted heroically when he saw a family of four in the wreckage of a car on the motorway.
Later, he appealed for help in tracking down the family to find out if they were okay.
He tweeted: "Just witnessed the most horrific crash on the M60. I ran to the car to see a family-of-four. I pulled a little girl and her father from the wreckage.
"Can everyone please retweet this in hope that it reaches the relations of the family, as I've tried to contact different hospitals in Manchester... but no luck so far.
"I hope they're all OK! Love Shayne."
He later added: "A very scary thing to witness."
The X Factor 2005 winner has not returned to social media since.
Shayne Ward (@shayneTward) June 26, 2015
The post has already been shared hundreds of times, but it's unknown if he has so far been able to track the family down.
Shayne will soon appear in Coronation Street as Aidan Connor, the cousin of Kym Marsh's character Michelle.
His first scenes are set to air over the summer.
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