Cricketer Freddie Flintoff is talking about his new role as a TV interviewer himself, as he begins his job grilling Hollywood stars for an Australian programme.
The Last Leg gang - Adam Hills, Josh Widdicombe, and Alex Brooker - will stop by to talk about the success of their show and how they're changed perceptions of disability. And Jo Brand will be discussing her epic Sport Relief challenge which saw her walk 135 miles across the country in a week.
Finally, music comes from Jason Derulo who also talks to Jonathan about his serious neck injury, and teaches the guests some street dance moves.
The Jonathan Ross Show, ITV, 9.20pm