He's joined by Gok Wan and Nick Luck, both part of Channel 4's presenting team for the Grand National.
They'll be discussing the festival and its fashions, as well as taking part in some equine-themed fun and games.
Russell Brand is also stopping by to chat about his latest film The Emperor's New Clothes, and Game Of Throne star Maisie Williams talks about her role in new movie The Falling.
Music comes from Nick Jonas who performs his new single, Jealous, live in the studio.
Alan Carr: Chatty Man Grand National Special, C4, 10pm