Joined by a live studio audience, the guys also welcome comedian Noel Fielding into their gang to go through the past seven days.
With viewers at home and in the studio encouraged to ask the question: Is it OK?, without fear of judgment or ridicule, the hosts delve into the minefield of sometimes difficult and delicate areas, and answer every question with their own unique insight. As well as one or two laughs.
The Last Leg, Channel 4, 10pm
Are you a fan of The Last Leg? Tell us below, as the best comment from across the website each week wins £50!