The 26-year-old told us at the Reveal Online Fashion Awards 2014 that he's looking to move on from the ITV2 show to focus on other projects.
"I'm going to leave soon," he said. "I think this may be my last series. I'm getting a bit bored of it, to be honest."
Mario added: "I have a few other business ideas I'd like to focus on."
The hunky star's comments came after it was revealed he's begun dating a new girl called Sophie who lives in Dubai. He's even flying back to see her in the coming weeks.
"I've had my fun and had a great time with my friends doing all the stuff boys should do at a young age," he recently said, "but now I'm ready to settle down and find the right person."
Settle down in Dubai, perhaps?
Maybe we're jumping the gun a bit, however, as Mario told us: "She not my girlfriend!"
If Mario does step away from TOWIE, he will just be the latest in a string of major castmembers to move on to other things.
Most recently, original star Sam Faiers announced she was taking a break from filming, while we've also said goodbye to favourites Lauren Goodger, Mark Wright, Joey Essex and Mario's ex-girlfriend Lucy Mecklenburgh.
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More photos from the Reveal Online Fashion Awards below:
Copyright: WENN Daniel Deme