And it's said to be the second time the TOWIE star has had a health scare since entering the house.
Sam, 24, was apparently taken out of the house and examined by a medical team earlier this week. After her check-up, Sam's condition worsened on Wednesday night and it was decided to take her to hospital yesterday.
A source tells today's Daily Star (25 January): "This is serious. Sam is really struggling. It's why she hasn't featured as much in the highlights as she would have if she was fully fit."
The newspaper says that Sam's face "ballooned up" after suffering an allergic reaction to something. She has also complained of a stomach ache.
Sam's mystery illness has been monitored by Big Brother and yesterday doctors decided to act after her condition worsened.
CBB producers have so far chosen NOT to mention Sam's illness on the daily shows, but Liz Jones mentioned Sam's illness when she was evicted earlier this week.
Liz said: "Sam is suffering in there. She has been accused of being quiet and not doing anything but there is a reason. She has been ill for more than two weeks.
"Some days she was so bad the producers let her stay in bed because she was really ill."
A Channel 5 spokesman confirmed Sam's visit to the hospital and told the newspaper: "While Sam was out of the house she was accompanied at all times by a member of staff who ensured that contact with the outside world remained at a minimum."
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