The theme for the first week is the 80s and there's another new twist as the show introduces the flash vote.
The lines will open after all the acts have sung for just under 10 minutes. They'll then close, the votes will be counted and the act with the lowest number of votes will be told there and then they're in the sing off on Sunday night. The lines then reopen and the remaining acts have to wait until the following evening to find out who else is in danger.
Nicole Scherzinger and her girls: Abi, Tamera, and Hannah will be hoping to wow, and Sharon's branded her overs 'divas', so can Sam, Lorna and Shelley strut their stuff on stage?
Louis Walsh has the boys, but will Luke, Nicholas and Sam make it through? Or will Gary's groups impress – Rough Copy, Kingsland Road and Miss Dynamix?
The X Factor, ITV, 8pm
Check out the glam makeovers for the top twelve acts below!
Copyright: Nicky Johnston/Thames/Syco