As leading lady in the comedy, it was only right that all eyes were on Anne, 32, as she sashayed down the red carpet in a beautiful, sheer black frock with beaded embellishments and feathered trim.
Gorgeous! Anne kept her dark hair swept to one side, finishing her look with a classic smoky eye and perfect pout.
The Oscar winner was joined by co-star Robert DeNiro. The Hollywood stars held hands on the red carpet, showing they struck up a close bond during filming.
The Intern tells the story of fashion CEO Jules (Anne) who ends up employing the elderly Ben (Robert) when her company signs up for a community outreach programme. It's directed by Nancy Meyers, who has previously worked on fab films including The Holiday, The Parent Trap and Father of the Bride.
In a recent interview with Refinery29, Anne admitted that she felt connected to her character, Jules.
"I don't always relate to my characters, but Jules I really did. It's hard to be a person making mistakes in the spotlight, and I related to her on that level. But she is someone who is handling her stress pretty well," she said.
"One thing that I love about Jules is she's a nice boss. She can be a little high-strung and she works everybody like crazy, but she is a nice boss."
The Intern is released in UK cinemas in 2 October.