The Strictly Come Dancing star will front a 4.5-mile walk through central London on Sunday, 8 May, starting and finishing at Cavendish Square, while taking in a string of the capital's biggest sights.
The event – celebrating The Year of the Brow - is part of fundraising efforts throughout May to raise money for two local charities that empower women and girls: Look Good Feel Better, which helps combat visible side effects of cancer treatment, and Refuge, which supports women and children escaping domestic violence.
Denise said: "I am truly proud to be a part of this year's Bold is Beautiful campaign. Our incredible UK charity partners, Look Good Feel Better and Refuge, support women and children undergoing serious times of adversity and help them to regain a sense of self and wellbeing.
"I've had the pleasure of meeting some of these women and have been humbled by their experiences. I urge everyone to get involved as we attempt to raise as much money as possible for this amazing cause!"
Those participating in the march will be treated to glamour stops throughout the route courtesy of Benefit, who will be touching up skin, lips, eyes and eyebrows all day. There's a whopping £20 worth of Benefit goodies available to collect throughout the march. A £10 donation is required to take part, which goes straight to one of the Bold Is Beautiful charities.
Meanwhile, throughout May, Benefit will be donating 100 per cent of profits from brow waxing services to the charities. Anyone booking a brow wax (£11.50) will receive a free full-size Gimme Brow kit worth £18.50.
The initiative has raised just under £2 million worldwide since its launch last year.
Find out how to get involved with Bold Is Beautiful here.